Would you like to participate in a research study for an investigational study drug to treat depression?
We are inviting you to take part in a research study for adults who have depression, are currently experiencing a depressive episode and have been unsuccessful in finding an anti-depressant treatment to sufficiently help their current depression symptoms.
The research study will be conducted at various study centers globally. You will visit a study center approximately 10-14 times over about 19 weeks during your participation. There is no cost to take part in the study. The investigational study drug and an approved antidepressant treatment, in addition to all study-related visits will be provided at no cost.
The MDD Clinical Trial is being conducted to assess how well the investigational study drug may work to treat participants with depression, in combination with an approved antidepressant treatment, who have been unsuccessful in finding an anti-depressant treatment to sufficiently help.
You may qualify for the MDD Clinical Trial if you:
- Are 18 to 65 years of age
- Are experiencing symptoms of depression or major depressive disorder
- Have been experiencing an episode of depression for at least 8 weeks and less than 2 years
- Have used at least 1 but not more than 3 antidepressant medications in your current depressive episode without sufficient improvement in your depression symptoms.
No health insurance is required.
Sign Up
What happens if I sign up? We will match you to a study center in your area that needs participants with depression or notify you when one becomes available. The study team will then contact you and you may have the opportunity to participate, if qualified.
If you think you might like to participate in the MDD Clinical Trial or would like more information, please enter your information below so we can see if you may qualify and can contact you about the studies. Keep in mind that participation is entirely voluntary. If you do decide to take part in a study, you may change your mind about participating at any time.
About Depression
Depression is a common mental health disorder that is either recurrent or chronic in many affected participants.
For many people, depression causes feelings of persistent sadness, loss of interest, and feelings of loneliness or emptiness.1 Major depressive disorder has a severe impact on overall functioning and is a leading cause of disability worldwide in terms of total years lost due to disability.2
There is no way to prevent depression. When people are diagnosed, a doctor may prescribe psychotherapy (talk therapy) as a treatment, while others see a medical intervention, like antidepressants, necessary to help treat the condition.
Despite the availability of numerous treatments (e.g., pharmacotherapy (medications), psychotherapy, electroconvulsive therapy [ECT]), achievement of consistent and favorable long-term outcomes still represents a significant unmet medical need.
This MDD Clinical Trial is being done to assess how well an investigational study drug works to treat participants with depression who have been unsuccessful in finding an anti-depressant treatment to sufficiently help.
Frequently Asked Questions
What is a clinical trial?
A clinical trial is a medical study that helps to answer important questions about an investigational drug – these may include how well an investigational study drug works for a certain condition. All medications must be tested in clinical research studies before they can be approved and prescribed to participants.
Why are clinical trials important?
A clinical trial is the process by which new and innovative medications, interventions and treatments are approved and brought to market, so people can live happier and healthier lives. Even over-the-counter medications, such as NSAIDs (e.g. Advil, Ibuprofen), you may have used to counteract a headache, have gone through the clinical research study process before it was available at your local pharmacy.
What is the purpose of the MDD Clinical Trial?
The MDD Clinical Trial is being done to assess how well an investigational study drug works to treat participants with depression who have been unsuccessful in finding an anti-depressant treatment to sufficiently help.
Study doctors want to compare the investigational drug to placebo, which looks like the investigational drug but contains no active medication. In this study, the term “study drug” refers to either the investigational medication or placebo.
What will the MDD Clinical Trial involve?
The MDD Clinical Trial will enroll about 900 participants with depression at approximately 75 study centers globally.
The study will include 10-14 follow-up visits for further assessment to a study center in your location over approximately 19 weeks.
If you qualify, you will be asked to take the study drug orally (by mouth) and an approved antidepressant treatment in the evening at bedtime at approximately the same time every day.
Will you receive compensation?
Participants who qualify to take part in the study may receive compensation for study related visits and travel. Please discuss this with the study team when they contact you.
Is there a cost to participate?
There is no cost to participate in the MDD Clinical Trial. If you qualify, you will receive all study-related care from a dedicated medical team and the study drug and an approved antidepressant treatment at no cost.
What else do you need to consider?
The research team will be able to explain more about what the MDD Clinical Trial will involve, and it is up to you to decide if you want to take part. Participation in this study is voluntary. Whether or not you decide to participate in this study will not affect your current or future relationships with your doctors. If you decide to participate, you are free to withdraw at any time without affecting those relationships.
How far is the study center?
We match you to a study center within a close travel distance from your home. If we are not running the study in your area currently, with your permission, we will keep your information in our database and reach out once a study in your area becomes available. If, at any time, you decided you no longer want your information stored, you can opt out and we will delete your details.
About the MDD Clinical Trial
The MDD Clinical Trial will enroll about 900 participants with depression at approximately 75 study centers globally.
The study will include approximately 10-14 follow-up visits for further assessment to a study center in your location over approximately 19 weeks.
Participants will receive all study-related care from a dedicated medical team and the study drug and an approved antidepressant treatment at no cost.
Participants may receive compensation for study related visits and travel.
The MDD Clinical Trial is being done to assess how well an investigational study drug works to treat participants with depression who have been unsuccessful in finding an anti-depressant treatment to sufficiently help. Study doctors want to compare the investigational drug to placebo, which looks like the investigational drug but contains no active medication. In this study, the term “study drug” refers to either the investigational medication or placebo.
Who can take part in the MDD Clinical Trial?
You may qualify for the MDD Clinical Trial if you:
- Are 18 to 65 years of age
- Are experiencing symptoms of depression or major depressive disorder
- Have been experiencing an episode of depression for at least 8 weeks and less than 2 years
- Have used at least 1 but not more than 3 antidepressant medications in your current depressive episode without sufficient improvement in your depression symptoms.